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Old 12-30-2009, 09:42 AM
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Default Magnesium oxide/hydroxide

Butyrate Improves Insulin Sensitivity and Increases Energy Expenditure in Mice
I found this paper after reading Stephan's blog here
Butyric Acid: an Ancient Controller of Metabolism, Inflammation and Stress Resistance

It may interest readers of this thread as it's partly to do with thermoregulation and energy burning.
Anyway in order to find out if it worked in humans or at least this human in particular I ordered some of These Butyraid 5$ Discount Code WAB666 and have been taking them the last couple of weeks. Certainly I've found they do seem to increase my ability to stay warm when everyone else is complaining about the cold, and yes despite it being the time of year when entertaining visitors inevitably leads to greater food/alcohol intake I'm actually losing weight although not actually eating any differenly than I normally do
You can see from picture A here that the butyrate mice had enhanced thermogenesis as a result of consuming butyrate.


I have to admit I haven't personally tried taking my temperature (particularly the method they used) while in the cold but I can report that despite the fact it's been very cold here I've been out every day and it's not bothered me and I usually find being cold particularly stressful. My partner likes sleeping with the window open and in winter I sometimes find I wake in the night freezing cold and have to find my sleeping socks and woolly hat but since the butyraid this hasn't happened.
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Old 12-30-2009, 11:25 AM
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Originally Posted by Ted_Hutchinson View Post
Anyway in order to find out if it worked in humans or at least this human in particular I ordered some of These Butyraid 5$ Discount Code WAB666 and have been taking them the last couple of weeks.
You should not take any product that contains magnesium oxide on a daily basis. Mag oxide is used by manufacturers; because it is very cheap.

When magnesium oxide is mixed with water, magnesium hydroxide is formed. As with all hydroxides, magnesium hydroxide is caustic and powerful free radical, and will burn healthy tissue.

Hydroxide reaches the intestines intact where it chemically burns the intestinal wall leading to inflammation, diarrhea, and increased risk of cancer. Take for example magnesium hydroxide (Milk of Magnesia), which is used as a laxative. The reason it works as a laxative is because after wiping out the stomach acid the excess magnesium hydroxide, being a very caustic chemical, chemically burns the intestinal wall leading to an influx of water in to the intestines as well as increased peristalsis. This is the same principle that causes the chronic diarrhea after the gallbladder is removed. The caustic bile also burns the intestinal wall, which increases the risk of intestinal cancer.

Instead, use butter. Or use a prebiotic, like inulin or all other soluble fibre, that feeds the friendly flora which make butyric acid. Like this: https://www.iherb.com/Jarrow-Formulas...der/15533?at=0
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Old 12-30-2009, 12:11 PM
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Ted, you may be hypothyroid if you are cold with cold feet and legs. I used to be like that until my naturopathic doctor added some T3 to the T4 that I take. Also, you might be surprised how much a tablespoon or two of coconut oil can warm the body. I learned to love taking it because I got one with good taste...Tropicana.

Another possibility is that the circulation in your legs needs checking or the heart is not pumping strong enough. Do you take CoQ10?
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Old 12-30-2009, 12:32 PM
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Originally Posted by jfh View Post
When magnesium oxide is mixed with water, magnesium hydroxide is formed. As with all hydroxides, magnesium hydroxide is caustic and powerful free radical, and will burn healthy tissue.

Hydroxide reaches the intestines intact where it chemically burns the intestinal wall leading to inflammation, diarrhea, and increased risk of cancer. Take for example magnesium hydroxide (Milk of Magnesia), which is used as a laxative.
Comparison of the effects of magnesium hydroxide and a bulk laxative on lipids, carbohydrates, vitamins A and E, and minerals in geriatric hospital patients in the treatment of constipation.In a crossover study the effects of magnesium hydroxide on serum lipids, carbohydrates, vitamins A and E, uric acid and whole blood minerals were compared with those of a bulk laxative containing plantago rind and sorbitol in 64 constipated, elderly long-stay patients, 55 of whom were receiving diuretics. Hypomagnesaemia occurred in 11 (17%) patients after bulk laxative and in two (2%) patients after magnesium hydroxide treatment. There was a slight reduction in low values of high-density lipoprotein cholesterol and high values of triglycerides after magnesium hydroxide treatment. There were no significant differences in plasma lipids, whole blood minerals or vitamins A and E using either laxative. Negative correlations were found between the increase in serum concentrations of magnesium and glycosylated haemoglobin A1 (P less than 0.02) and the serum level of uric acid (P less than 0.01). These results suggest that the long-term effects of magnesium hydroxide and bulk laxative on the absorption of nutrients may not be significantly different.
Magnesium hydroxide, however, may have beneficial effects on lipid disorders, impaired glucose tolerance and hyperuricaemia in magnesium deficiency due to diuretics and thus may be a favourable laxative for use in bedridden geriatric patients receiving diuretics.


Mother was Right: The Health Benefits of Milk of Magnesia
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Old 12-30-2009, 01:32 PM
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Default Magnesium oxide/hydroxide

I hope you don't mind that I copied your reply to a separate thread, instead of hijacking the other one Ted.

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Originally Posted by Ted_Hutchinson View Post
Comparison of the effects of magnesium hydroxide and a bulk laxative on lipids, carbohydrates, vitamins A and E, and minerals in geriatric hospital patients in the treatment of constipation.In a crossover study the effects of magnesium hydroxide on serum lipids, carbohydrates, vitamins A and E, uric acid and whole blood minerals were compared with those of a bulk laxative containing plantago rind and sorbitol in 64 constipated, elderly long-stay patients, 55 of whom were receiving diuretics. Hypomagnesaemia occurred in 11 (17%) patients after bulk laxative and in two (2%) patients after magnesium hydroxide treatment. There was a slight reduction in low values of high-density lipoprotein cholesterol and high values of triglycerides after magnesium hydroxide treatment. There were no significant differences in plasma lipids, whole blood minerals or vitamins A and E using either laxative. Negative correlations were found between the increase in serum concentrations of magnesium and glycosylated haemoglobin A1 (P less than 0.02) and the serum level of uric acid (P less than 0.01). These results suggest that the long-term effects of magnesium hydroxide and bulk laxative on the absorption of nutrients may not be significantly different.
Magnesium hydroxide, however, may have beneficial effects on lipid disorders, impaired glucose tolerance and hyperuricaemia in magnesium deficiency due to diuretics and thus may be a favourable laxative for use in bedridden geriatric patients receiving diuretics.


Mother was Right: The Health Benefits of Milk of Magnesia
I'm still convinced that mag oxide is not for any duration.

Quote:
[A case of the milk-alkali syndrome with a small amount of milk and magnesium oxide ingestion--the contribution of sustained metabolic alkalosis induced by hypertonic dehydration]

Yamada T, Nakanishi T, Uyama O, Iida T, Sugita M.

Fifth Dept. of Internal Medicine, Hyogo College of Medicine.

We described a patient with the milk-alkali syndrome induced by the ingestion of small amount of milk (200 ml/day) and ice cream (145 g/day) and the administration of small dose of absorbable alkali (magnesium oxide 2.0 g/day) for the treatment of chronic constipation. The present case shows not only triads, i.e., hypercalcemia (s-Ca 14.3 mg/dl), metabolic alkalosis (s-HCO3- 37.4 mEq/L), and renal insufficiency (s-Cre 2.3 mg/dl) but also hypernatremia (s-Na 161 mEq/L) and hypertonic dehydration after the frequent episodes of elevated body temperature. The milk-alkali syndrome has been defined as the hypercalcemia with a metabolic alkalosis from a high amount of calcium intake and long term administration of absorbable alkali in any form, usually as calcium carbonate for the treatment of peptic ulcer. As the present case could be distinguished from any other cases previously reported with regard to the amount of calcium (0.4 g/day) and alkali (36 mEq/day) intake and the clinical situations that induced the syndrome, we compared the present case with the previous reports, calculating the amount of calcium and alkali intake from milk and absorbable alkali. After the introduction of the H2 blockers for peptic ulceration, the most cases with milk-alkali syndrome had provoked by the smaller amount of calcium than previously reported, which were associated with the treatment of relatively large amount of alkali (50-150 mEq/day), suggesting the role of sustained metabolic alkalosis for the development. In the present case the metabolic alkalosis induced by hypertonic dehydration and enhanced by absorbable alkali intake also could cause an increase of renal tubular reabsorption of calcium and a decrease of ionized calcium which might produce increased secretion of parathyroid hormone followed by vitamin D3 activation and increased Ca absorption from the gut. The metabolic alkalosis might be essential to the development of the milk-alkali syndrome without a high calcium and absorbable alkali intake.

PMID: 1920938 [PubMed - indexed for MEDLINE]

https://www.ncbi.nlm.nih.gov/pubmed/1...ubmed_RVDocSum
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Old 12-30-2009, 09:36 PM
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Since Jim started a new thread, I moved related posts here to keep both threads on topic.
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Old 01-08-2010, 03:38 PM
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Assuming sufficient stomach acid and taking Mg Hydroxide in teh form of milk of magnesia, you should be fine.
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Old 01-08-2010, 08:29 PM
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Question Magnesium OXIDE supplement question

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Originally Posted by jfh View Post
You should not take any product that contains magnesium oxide on a daily basis. Mag oxide is used by manufacturers; because it is very cheap.

When magnesium oxide is mixed with water, magnesium hydroxide is formed. As with all hydroxides, magnesium hydroxide is caustic and powerful free radical, and will burn healthy tissue.

Hydroxide reaches the intestines intact where it chemically burns the intestinal wall leading to inflammation, diarrhea, and increased risk of cancer.
I have 2 bottles on order from Swanson vitamins of "Triple Magnesium Complex". It says it has the three most recommended forms of magnesium for optimum absorption.

They are 400 mg capsules, 350 mg. magnesium OXIDE, 40 mg. of magnesium citrate, and 10 mg magnesium aspartate.

Are there dangers in taking this product daily as a magnesium supplement?
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Old 01-09-2010, 02:08 AM
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I have 2 bottles on order from Swanson vitamins of "Triple Magnesium Complex". It says it has the three most recommended forms of magnesium for optimum absorption.

They are 400 mg capsules, 350 mg. magnesium OXIDE, 40 mg. of magnesium citrate, and 10 mg magnesium aspartate.

Are there dangers in taking this product daily as a magnesium supplement?
I don't think so. Magnesium Oxide has been used by health professionals in hospitals for many years. I agree that it is NOT the best form of magnesium and many people don't absorb it BUT at the levels in those magnesium tablets it won't be harmful. There is a huge difference between 2g daily Magnesium Oxide and 40mg.

Here are some good magnesium resources.
Magnesium Chloride

Krispin on Magnesium

MGWATER
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Old 01-09-2010, 08:35 AM
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I don't think so. Magnesium Oxide has been used by health professionals in hospitals for many years. I agree that it is NOT the best form of magnesium and many people don't absorb it BUT at the levels in those magnesium tablets it won't be harmful.
Thanks for your input Ted! I was using Magnesium Malate and Magnesium Taurate for a long time. My last Magnesium was Citrate. I've been trying to save some money on supplements, I take many and can't afford to keep taking them all. This Triple Magnesium Complex was on sale, buy one get one free. I paid $3.99 for a total of 200 capsules. Next time I'll be sure to pay attention to the form I'm buying.
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Old 01-13-2010, 05:25 AM
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Mag Taurate has great success in preventing certain cardiac arrythmias. As a chemist, I do not understand why taurate does and citrate does not, but for some reason, the form of the mineral does make a difference.
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Old 01-13-2010, 06:46 AM
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If I take more than 250 mg of magnesium oxide it sends me straight to the bathroom within a very short time. I believe the usual requirement is 400 mg or more. Minerals are hard to absorb so anyone with a deficiency would likely need more.
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Old 01-13-2010, 07:13 AM
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If I take more than 250 mg of magnesium oxide it sends me straight to the bathroom within a very short time. I believe the usual requirement is 400 mg or more. Minerals are hard to absorb so anyone with a deficiency would likely need more.
Probably because Mg Oxide will gel up somewhat in your gut. It might be better to chew the tablet or take milk of mag in a glass of water.
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Old 01-13-2010, 03:24 PM
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Magnesium oxide is poorly absorbed by the body.

Better to use magnesium from citrate.

...and yes, 400 mg per day is what we need, however most get less than half of that amount. The reason is mainly because the soil is depleted of magnesium, therefore whatever grows there will also be depleted of magnesium.
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Old 01-13-2010, 04:47 PM
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If I remember right, they used to say that the brown wilted areas on the inner leaves of lettuce are a sign of magnesium deficiency. Adelle Davis used to say, "What carrot grown where?"....when asked how nutritious they were. Our food doesn't have hardly any nutrition anymore by the time it gets to the grocery store.

I owe you a long reply on another thread pinballdoctor, and I appologize for taking so long, but right now I'm nodding off to sleep so need a nap.
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