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Old 11-29-2010, 10:29 AM
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Default Making gold nanoparticles - a real breakthrough?

I found this scientific paper that showed how, using off-the-shelf cinnamon powder, one can generate gold nanoparticles from a gold salt without any expensive lab equipment or electrolysis. In my view, this might also work for producing silver nanoparticles, and if it does, it would enable the production of very high quality colloidal silver solutions without electricity, CS generators, or the expense of purchasing the solutions from vendors. Besides, colloidal gold can be helpful by itself!

Journal is Pharmaceutical Research

Quote:
An Effective Strategy for the Synthesis of Biocompatible Gold Nanoparticles Using Cinnamon Phytochemicals for Phantom CT Imaging and Photoacoustic Detection of Cancerous Cells

Nripen Chanda, Ravi Shukla, Ajit Zambre, Swapna Mekapothula, Rajesh R. Kulkarni, Kavita Katti, Kiran Bhattacharyya, Genevieve M. Fent, Stan W. Casteel and Evan J. Boote, et al.
Quote:
Six mL of doubly deionized (DI) water was added to a
20 mL vial, followed by the addition of 25 mg of cinnamon.
The mixture was stirred continuously at 25�C for 5 min.
Then, 100 μL of 0.1 M NaAuCl4 solution (in DI water)
was added. The color of the mixture turned purple-red
within 20 min after the addition of NaAuCl4, indicating the
formation of gold nanoparticles. The reaction mixture was
stirred additionally for 10 min. The gold nanoparticle
solution was separated from the residual cinnamon powder
by means of a standard filter paper. The solution was
further filtered through a 0.5 micron filter. The gold nanopaticles
were characterized by UV-Vis absorption spectroscopy
and Transmission Electron Microscopy (TEM) analysis.

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Old 11-29-2010, 11:49 AM
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Further research has indicated to me that silver nanoparticles can be generated in a similar manner using silver nitrate and cinnamon powder dispersed in double-deionized water as starting ingredients. Unfortunately, the definitive paper is available only for a fee, but the free alternatives indicate that it can, and has, been done. This is really important as it eliminates the need for a CS generator to produce high quality colloidial silver (an aqueous solution of silver nanoparticles) by using a totally "green" method (a natural substance, cinnamon powder).

This confirms a belief I hold, and that is that real medical solutions are natural and accessible to all, without regard to financial status or intellectual ability. If one can make high quality colloidal silver using inexpensive silver nitrate and cinnamon powder, then that makes this remedy available to all, not just to those who can afford a CS generator. And, this procedure generates real nanoparticles, not just silver ions.

Last edited by LariAnn; 11-29-2010 at 11:52 AM. Reason: additional information
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Old 11-29-2010, 03:29 PM
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What works for metal A will not necessarily work for metal B and visa versa. To stabilize a small particle, you need it at a certain pH and the pH value will be different for silver and gold.
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Old 11-30-2010, 08:51 AM
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I acknowledge that different metal salts may require different processing protocols, but this is not up for discussion because the applicable research is a fait accompli and the results are in. Nanosilver can be made from silver salts using cinnamon or other natural products, such as lotus (Nelumbo) leaves. Not all the research papers are open access, however.

My reason for posting this was to get the information out to the people who might wish to make use of it, people who might otherwise not even imagine that such a thing might be possible, or have been done. The protocol for gold nanoparticles is so simple that you don't need a lab or to do it, while by contrast, producing colloidial gold consisting of nanoparticles via the industrial method requires very expensive equipment. This requirement took it out of the hands of the home do-it-yourselfer, until now.
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Old 11-30-2010, 09:05 AM
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Here's one of the references where silver nanoparticles were produced as I've described above:

Cinnamon zeylanicum bark extract and powder mediated green synthesis of nano-crystalline silver particles and its bactericidal activity

Colloids and Surfaces B: Biointerfaces
Volume 73, Issue 2, 15 October 2009, Pages 332-338






References and further reading may be available for this article. To view references and further reading you must purchase this article.


M. Sathishkumara, K. Snehaa, S.W. Wona, C.-W. Choa, S. Kima and Y.-S. Yun


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Old 11-30-2010, 09:22 AM
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Quote:
Originally Posted by LariAnn View Post
I acknowledge that different metal salts may require different processing protocols, but this is not up for discussion because the applicable research is a fait accompli and the results are in. Nanosilver can be made from silver salts using cinnamon or other natural products, such as lotus (Nelumbo) leaves. Not all the research papers are open access, however.

My reason for posting this was to get the information out to the people who might wish to make use of it, people who might otherwise not even imagine that such a thing might be possible, or have been done. The protocol for gold nanoparticles is so simple that you don't need a lab or to do it, while by contrast, producing colloidial gold consisting of nanoparticles via the industrial method requires very expensive equipment. This requirement took it out of the hands of the home do-it-yourselfer, until now.

I am talking about the stabilization of the particles in solution. There is a relatively narrow pH range and the pH range for silver may not be the same for gold.
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Old 11-30-2010, 03:51 PM
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If I'm not mistaken, pH applies more to ionic solutions, not to nanoparticle colloids. pH has to do with the presence of positive acid ions (H+) or negative alkaline ions (OH-); since nanoparticles are the actual metal, not ions, the pH of the solution should not change with their presence. Therefore, if the water used in the production process is essentially pH neutral, it should remain so after the nanoparticles have been produced because there is no ionic dissociation occurring. The only other consideration would be the pH of the metal salt solution prior to processing, but if a buffered solution is used, pH should not be an issue there either.
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