08-03-2007, 09:59 AM
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Lecturer
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Join Date: Apr 2006
Location: Propecia, CA
Posts: 1,851
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Vitamins May Improve Mood in the Elderly
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The new prospective, double-blind, placebo-controlled study, recruited 225 hospitalised acutely ill older people (average age 75.6, average BMI 25.2 kg per sq. m) and randomly assigned them to receive either normal hospital diet plus multivitamin and mineral (MVM) supplements (providing 100 per cent of the Reference Nutrient Intakes for a healthy old person for vitamins and minerals) or normal hospital diet plus placebo for six weeks.
Depressive symptoms and cognitive function were assessed using the 15-item geriatric depression questionnaire (GDS) and abbreviated mental test questionnaire (AMT), respectively.
Gariballa and Forster report that at the end of the study levels of folate and vitamin B12 in red blood cells and the plasma, respectively, increased significantly in the MVM group but decreased in the placebo group.
Significant differences were also reported for symptoms of depression scores between the groups, with beneficial effects observed for patients in the supplementation group regardless of the initial level of depression of the individual, ranging from no depression to severe depression. No differences in cognitive function scores.
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Vitamin Supplementation and Depression in the Elderly
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