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				 Ganoderma information 
 
			
			Ganoderma lucidum - Reishi Mushrooms
 Ganoderma lucidum (Ling Zhi) is documented to have wonderful medicinal value.
 Reishi mushrooms have been used in traditional Chinese medicine as a herbal
 medicine for more than 5,000 years, making it one of the oldest mushrooms known
 to have been used in medicine.
 
 The word ling zhi, in Chinese, means "herb of spiritual potency" and is
 considered the "mushroom of immortality". It has attained a reputation in the
 East as the miracle mushroom due to its many health benefits and absence of
 side-effects. Ling zhi has been added to the American Herbal Pharmacopoeia and
 Therapeutic Compendium.
 
 Ling zhi has a diverse amount of other species and mycologists are still
 researching the differences between each particular Ganoderma lucidum species.
 Ganoderma lucidum is the only known source of a group of triterpenes, known as
 ganoderic acids, which have a molecular structure similar to steroid hormones.
 It is a source of biologically active polysaccharides, ergosterol, coumarin,
 mannitol, lactones, alkaloids, unsaturated fatty acids and vitamins and
 minerals.
 
 The reishi extract has been shown to be effective in treating migraine
 headaches. It is believed that oxygen shortage in the brain (hypoxia) is at the
 core of the pathogenesis of a migraine attack.
 
 As an anti-inflammatory agent, the extract is effective in substantially
 alleviating the problems and pain related to rheumatism or osteoarthritis and
 gout.
 
 In treating hypertension or hypotension the extract has been shown to be highly
 effective in a very large number of cases treated. In the more successful cases
 blood pressure is back to normal within 2 months.
 
 The extract has been found effective in reducing and in some cases eliminating
 asthma attack.
 
 The extract is effective in reducing blood sugar levels and the amounts of
 insulin required for diabetic patients.
 
 The extract is effective in regaining stamina and energy or debility due to
 prolonged illness especially for cancer patients after undergoing radio and/or
 chemotherapy. They are able to eat and sleep well.
 
 The extract is effective in clearing up a large variety of skin allergic
 conditions either due to food or airborne allergens.
 
 Ganoderma extract has been found to be useful in detoxifying the kidneys and
 improving its overall function. Patients receiving hemodialysis should find that
 the duration and frequency of the treatment could be reduced.
 
 The extract has been shown effective in reducing or eliminating excessive
 menstrual pain and irregularities.
 
 Ganoderma extract has been found effective in addressing a variety of
 cardiovascular problems. It improves the circulatory system with excess oxygen.
 It also decreases the conditions of angina pectoris and palpitation.
 
 
 Andrew Pacholyk, MS, L.Ac
 
 
 References
 
 1. ^ Paterson RR (2006). "Ganoderma - a therapeutic fungal biofactory".
 Phytochemistry 67: 1985�2001. doi:10.1002/chin.200650268.
 2. ^ Medicinal Mushrooms: An Exploration of Tradition, Healing, & Culture
 (Herbs and Health Series)by Christopher Hobbs (Author), Harriet Beinfield
 3. ^ Chinese Herbal Medicine: Materia Medica, Third Edition by Dan Bensky,
 Steven Clavey, Erich Stoger, and Andrew Gamble (2004)
 4. ^ David Winston and Steven Maimes Adaptogens 2007
 5. ^ Medicinal Mushrooms: An Exploration of Tradition, Healing, & Culture
 (Herbs and Health Series)by Christopher Hobbs (Author), Harriet Beinfield
 6. ^ Chinese Herbal Medicine: Materia Medica, Third Edition by Dan Bensky,
 Steven Clavey, Erich Stoger, and Andrew Gamble (2004)
 7. ^ David Winston and Steven Maimes Adaptogens 2007
 8. ^ Li YQ, Wang SF (2006). "Anti-hepatitis B activities of ganoderic acid
 from Ganoderma lucidum". Biotechnol. Lett. 28: 837�841.
 doi:10.1007/s10529-006-9007-9.
 9. ^ Gao Y, Gao H, Chan E, Tang W, Xu A, Yang H, Huang M, Lan J, Li X, Duan W,
 Xu C, Zhou S. Related Articles, Links Abstract Antitumor activity and underlying
 mechanisms of ganopoly, the refined polysaccharides extracted from Ganoderma
 lucidum, in mice. Immunol Invest. 2005;34(2):171-98
 10. ^ Cheng JJ, Zeng YS, Xiong Y, Zhang W, Chen SJ, Zhong ZQ. Division of
 Neuroscience, Department of Histology and Embryology, Zhongshan Medical College,
 Sun Yat-sen University, Guangzhou Ganoderma spores may regulate the levels of
 mitochondria-related molecular substances in hippocampus of young rats birthed
 by rats with gestational hypertension.Zhong Xi Yi Jie He Xue Bao. 2007
 May;5(3):322-7.
 11. ^ Stavinoha, W. (1993). Short term dietary supplementation with ganoderma
 lucidum slows development and growth of microadenomatous lesions in the colon of
 rats treated with the carcinogen 1,2 dimethylhydrazine. Presented at the 5th
 international symposium on ganoderma lucidum, Seoul, Korea on June 17, 1993.
 12. ^ Hijikata Y, Yasuhara A, Sahashi Y. Related Articles, Links Abstract
 Effect of an herbal formula containing Ganoderma lucidum on reduction of herpes
 [[zoster pain: a pilot clinical trial. Am J Chin Med. 2005;33(4):517-23. PMID:
 16173526 [PubMed - indexed for MEDLINE]
 13. ^ Chinese Herbal Medicine: Materia Medica, Third Edition by Dan Bensky,
 Steven Clavey, Erich Stoger, and Andrew Gamble (2004)
 14. ^ David Winston and Stephen Maimes. Adaptogens 2007
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 polysaccharides from some polyporaceae, Ganoderma applanatum (Pers.) Pat and
 Phellinus linteus (Berk. et Curt) Aoshima.Chem Pharm Bull (Tokyo). 1971
 Apr;19(4):821-6. PMID: 5087927
 16. ^ Yang, QY and Wang, MM. (1995). The effect of ganoderma lucidum extract
 against fatigue and endurance in the absence of oxygen. In Proc. Contributed.
 Symposium. 59A, B.2. Role of Ganoderma Supplementation in Cancer Management
 17. ^ Miyamoto, T., Abe, T., Hasunuma, K. (1985). Japan Kokai Tokkyo Koho
 JP60, 199,80 [85,199.810] (CI. A61K7/06). Appl. 84/5,977. 24 March 1984.
 18. ^ Jia, YF., Zhou, XB., Meng, H., and Zhang, LX. Effects of Ling-Zhi on
 hemopoietic system in mice - immunopharmacological study (11). In The research
 on ganoderma (part I). Zhu S. and Mori M. (eds). Shanghai Med. U. Press,
 Shanghai, P. 284-288
 19. ^ Shi, JH. (1993). PSP for the protection of the tumorous patients during
 chemotherapy. In 1993 PSP Intl Symposium, Yang QY and Kwok CY (eds.), Fudan U.
 Press, Shanghai, p.271-2
 20. ^ Chang, R. (1994). Effective dose of ganoderma in humans. In Proc.
 Contributed Symposium 59A, B. 5th Intl. Mycol. Congr., Buchanan PK, Hseu RS and
 Moncalvo JM (eds), Taipei, p. 101-13.
 21. ^ Lee, SS., Chen, FD., Chang, SC., et al. (1984). In vivo anti-tumor
 effects of crude extracts from the mycelium of ganoderma lucidum. J. of Chinese
 Oncology Society 5(3): 22-28.
 22. ^ Suga, T., Shiio, T., Maeda, YY., Chihara, G. (1994). Anti tumor activity
 of lenytinan in murine syngeneic and autochthonous hosts and its suppressive
 effect on 3 methylcholanthrene induced carcinogenesis. Cancer Res. 44:5132-
 23. ^ Taguchi, T.(1987). Clinical efficacy of lentinan on patients with
 stomach cancer: end point results of four-year follow-up survey. Cancer
 Detection & Prevention. Suppl. 1:333-49.
 24. ^ Mitomi, T., Tsuchiya, S., Iijima, N., et al. (1992). Randomized control
 study on adjuvant immunochemotherapy with PSK in curatively resected colorectal
 cancer. Diseases of the Colon & Rectum. 35(2):123-30.
 
 25. Stanley G, Harvey K, Slivova V, Jiang V and Sliva D. Ganoderma lucidum
 supresess angiogenesis through the inhibition of secretion of VEGF and TGF-beta
 from prostate cancer cells. Biochem Biophys Res Commun 2005; 330:46-52
 
 26. Cao QZ and Lin ZB. Antitumor and anti-angiogenic activity of Ganoderma
 lucidum polysaccharides peptide. Acta Pharmacol Sin 2004; 25: 833-8
 
 27. Jian J, Slivova V, Valachivocova T, Harvey K and Sulva D. Ganoderma lucidum
 inhibits proliferation and induces apoptosis in human prostate cancer cells
 PC-3. Int J Oncol 2004; 24:1093-9
 
 28. Hu H, Ahn NS, Yang X, Lee YS and Kang KS. Ganoderma lucidum extract induce
 cell cycle arrest an apoptosis in MCF-7 human breast cancer cell. Int J Cancer
 2002; 20:250-3
 
 29. Hsu MJ, Lee SS and Lin WW. Polysaccharide purified from Ganoderma lucidum
 inhibits spontaneous and Fas-mediated apoptosis in human neutrophils trough
 activation of the phosphatidylinositol 3 kinase/akt signaling pathway. J Leukoc
 Biol 2002;72:207-16
 
				__________________"We can judge the heart of a man by his treatment of animals." ~Immanual Kant~
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