Don't know if any of you have heard of this protocol before, but in my opinion, it is ridiculous and and dangerous. Risks quoted from link below include:

Major risk of Addison Syndrome (5%-25% of CFS that complete the protocol)
Increased risk (100 300%) of Heart Attack
Increased risk (100+%) of Cancer (Breast, Colon and Prostate are well documented)
Increased risk (67+%) of Multiple Sclerosis
Increased risk (400+%) of Diabetes
Increased risk of Depression
Increased risk (500+%) of Osteoarthritis and Osteoporosis
Increased risk of nephrotic syndrome, schizophrenia and severe bipolar disorder.
Increased risk of Hyperparathyroidism
Increased risk of Crohn Disease and Sjogren's syndrome
Increased risk of Rheumatoid Arthritis
Increased risk of Systemic Lupus Erythematosus
May cause fetal and neonatal morbidity and death
Risk of Angioedema

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"The Marshall Protocol was developed by Trevor Marshall, PhD, in 2002 to treat certain diseases that involve Th1 immune system dysfunction.

Dr. Marshall's papers describe how numerous Th1 diseases such as sarcoidosis, Lyme disease, chronic fatigue syndrome, fibromyalgia, lupus and rheumatoid arthritis (among others) are caused by Cell Wall Deficient (CWD) bacteria of various species......

An essential part of the Marshall Protocol is avoidance foods and vitamin supplements containing vitamin D to reduce the level of this hormone which suppresses the immune system......

A key part of the protocol is the establishment of an inflammatory blockade of the hormone Angiotensin II with an Angiotensin Receptor Blocker (ARB), Benicar (olmesartan medoxomil).

The protocol also includes the introduction of carefully, selected low dose antibiotics in a pulsed schedule"......

https://www.marshallprotocol.com/forum2/364.html

"Ingested Vitamin D is an immune-suppressant, similar to the function that prednisone performs. Ingested Vitamin D suppresses the action of the VDR (Vitamin D Receptor) and thus turns-off the immune system's Th1 response so it cannot fight the intra-phagocytic bacteria. People feel better in the short-term, but will succumb to the infection more rapidly in the long-run"......

https://www.marshallprotocol.com/forum2/4062.html

"The MP coordinates the use of Benicar (Olmesartan medoxomil), and specific, pulsed, low-dose, bacteriostatic, oral antibiotics to enable the immune system to destroy the persistent bacteria [5]. Correctly dosed, Benicar reduces inflammatory cytokine production by blocking the angiotensin II, type I receptors to inhibit, inter alia, the release of tumor necrosis factor-alpha during the Th1 immune reaction"......

https://autoimmunityresearch.org/phase1.pdf

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This treatment protocol goes against so many known facts about the importance of Vitamin D it's not even funny. I also do not believe that Vitamin D suppresses the immune system. I wondered what Dr Paul Cheney, who has done much research on CFIDS, Fibro and other such ailments would have to say about this protocol. I found the answer to that.... he seems to be very much against it.

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Dr Cheney, MD, writes:

"I'm concerned that an ARB (Angiotensin Receptor Blocker) is being used in CFIDS patients [via MarshallProtocol.com] without an awareness of its effect on "Q."

Big issue [with MarshallProtocol.com]! If you block AT1 with an ARB [like Benicar], down will go your Aldosterone, and down will go your blood volume, and you could be in a heap of trouble [i.e. Addison Syndrome]. ARBs that bind to AT1 will constrict blood volume [which is unhealthy with PWCs].

I'm also concerned that the other receptor [AT2] is being ignored. No one knows what it does. Not even Merck! I suspect that it has an immune effect. An ARB like Benicar selectively binds very tightly to AT1, resulting in a two�to three-fold increase of Angiotensin II, which then binds to the wide-open AT2 receptor. And who knows what kind of immune responses that is setting off. This is just speculation, but I am concerned [over the safe use of Benicar for CFS].

"I don't believe that you can block a regulatory pathway [with Benicar],..... you[MarshallProtocol.com] have no idea what that thing is doing and then hope that down the road everything will be rosy."

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Go to the following link to read the bizarre quotes of this Dr Marshall and a nurse on his forum, dodging the question of possible risks of using his protocol, and some facts and links regarding the importance of Vitamin D:

https://lassesen.com/cfids/MarshallProtocolRisks.htm

The Marshall Protocol is proving to be a very successful treatment for all sorts of chronic disease. The success rates are higher than any conventional treatment can even dream of claiming. Read just some of the success stories thus far:

https://tinyurl.com/2pm37t
https://www.carouselcharts.com/Transc...coveryLAX2.pdf
https://winmlm.neostrada.pl/mp/townse...2007.Part2.pdf
https://bacteriality.com/category/interview-patient/

(Oh, did I neglect to say? All these success stories, without exception, only happened because every ill patient eliminated Vitamin D from his/her diet)

And remember this .... it was in 1982 when Drs Barry J. Marshall and J. Robin Warren discovered that ulcers were caused by Helicobacter pyloribacteria and not stress and lifestyle as was previously thought (doesn't say much for the efficacy of prior research that came to the silly conclusions) and they were laughed at by conventional medicine and faced criticism much like the nay-sayer post before this one. In 2005, they won the Nobel Prize in Medicine for their discovery. The same will be repeated for Dr Trevor Marshall, mark my words - they are already laughing at his discoveries surrounding the immunosuppressive effects of the secosteroid we call "Vitamin D" and the effects on the VDR (Vitamin D Receptor) and innate immune system. As with B Marshall and R Warren, T Marshall will have his day in Stockholm.

Here is some information re the Vitamin D discoveries:

https://www.prweb.com/releases/2008/1/prweb639651.htm
https://trevormarshall.com/BioEssays-...l-Preprint.pdf
https://bacteriality.com/2007/09/15/vitamind/

Having said this, no one ever said Marshall's protocol would be easy. Unfortunately, the immunopathology (herxheimer) is unavoidable. Kill the bacteria and everyone, without exception, feels increased symptomatology from the release of endotoxins. Those with heavy bacterial load and are sicker will likely feel it more and have more difficulty. It takes commitment and compliance. Many don't properly comply (e.g., especially with light exposure) and they pay the price. Those who are committed and compliant will eventually achieve recovery. Good luck!

Hola Amigo,

I've spent some time on lyme forums and it seems that this marshall protocol does not work for everyone. Have you had success with it?

Really, it would scare me to interrupt the Vitamin D pathways.

Can you tell me what this is? Cell Wall Deficient (CWD) bacteria of various species

Hey, and welcome to to the forum.

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This is not medical advice. Just opinion. Whatever you decide to do your your health is strictly your business and your choice.
Visit www.HealthSalon.org

Yes, I've had some success with it, although I'm not yet done. So has someone else I know. The treatment is not easy and takes patience, dedication and compliance. Not everyone has what it takes.

https://www.marshallprotocol.com/forum32/1146.html
https://www.marshallprotocol.com/forum32/1584.html

Vitamin D:
https://bacteriality.com/2007/09/15/vitamind/

Cell wall deficient organisms:
https://bacteriality.com/2007/08/15/l-forms/
https://bacteriality.com/2008/05/26/biofilm/
https://www.marshallprotocol.com/forum2/2810.html

https://bacteriality.com/2007/08/15/l-forms/

haven't had time to look at all this but I did look at this site.
I see several problems.
Yes, estrogen replacement therapy has caused severe disease but just look at the crap they were giving to women. Not based on lab values for need, not an identical molecule, not balanced with progesterone. Their case is filled with holes.

So then they want you just to automatically shift over into their vit D theory. First of all I am seeing quite a few vit d deficient people. Second of all I have been on high dose vit D for a few weeks and am seeing some good progress in a skin condition.

Off hand it sounds like hooey to me about the vitamin D

Then this one: https://bacteriality.com/2007/08/15/l-forms/
Seems to me that MMS is taking care of many of these type of microbes. A number of lyme people are responding quite well to mms who have lyme. As well as ulcerative colitis, crohns.

And then this one: https://bacteriality.com/2008/05/26/biofilm/
Biofilms are everywhere and not knew. Why do some become victims and other don't?
There is a system of treatment for biofilms called phage therapy. They cure the worst MRSA with it and other disease as well. It use to be available in this country until pennicillin happened. Thank god Russia had the foresight to preserve the work.
Those who are most susceptible are those with the weakest immune systems or a system that just can't cope with a particular foreign bug. Why are some people MRSA carriers but never get the mrsa disease?

I will keep my vitamin D, thank you.

I would say that if the Marshall protocol does not cure you it will kill you. I haven't seen any testimonials where people were cured of Lyme with this protocol. If so show me. I have only seen, feeling a bit better and now back to work. Not cured.

__________________
This is not medical advice. Just opinion. Whatever you decide to do your your health is strictly your business and your choice.
Visit www.HealthSalon.org

I've also had successes on the Marshall Protocol. I remember when my specialist first prescribed the treatment for me, I went online and read those same stats you posted. But I never did find any sources to back up those stats and the only thing I did see was that there were many very ill people slowly recovering on this protocol.

I have been on the Marshall Protocol for almost a year and everything from Neuropathy to Bipolar has almost disappeared....i am glad I studied the science which is based on REALITY, not a lot of mis-information about Benicar and Vitamin D....Which is not a nutrient.I think what's really ridiculous is making statements about a science you obviously don't understand.