Depression: an inflammatory illness?

pinballdoctor

\r\n \r\n You can easily see if magnesium is present in vegetables, because the more the magnesium, the greener the veggie.. and have you noticed over the last few years how much paler the green is becomming?
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\nWhen I was a kid, celery was a very dark green, as was broccoli and carrot tops... and now they look alot lighter .
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\nThe next time you are in the supermarket, look at the celery. They will be several shades of green, and I would suggest buying the darkest green ones..
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\nRegarding inflammation, most disease is associated with inflammation, however this is a symptom not the cause. After all, something has to cause the inflammation...either as a body defence mechanism, perhaps an organism or mycotoxin, or an allergic reaction, etc., however all can be traced back to a deficiency of an essential nutrient.
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\nMost people are deficient in magnesium, iodine, and vitamin D, however, there are 90 essential nutrients, so is is likely most people are deficient in several..\r\n

pinballdoctor

\r\n \r\n Doctor Hoffer showed years ago that depression, as well as several mental issues, were vitamin B deficiency... sometimes thiamine, niacin, and/or B12.
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\nSome bypolar "specialists" use trace minerals such as lithium, however using just this or that isn\'t good enough since these nutrients work together, thus all 90 are needed.\r\n

happy2bhere · 05:48 AM

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D Bergy

\r\n \r\n When I was diagnosed with Crohn\'s Disease I accidentally cured my depression.
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\r\nI started taking Krill Oil, Ginger, and Larger doses of Turmeric to quell the inflammation associated with the disease. A few months later my wife said "you have not had any depression lately". She always knew first when I was going into a funk. I thought about it and realized I never had gone a month without depression since I was a teenager. Since I was forty something at the time, that really was unusual.
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\r\nLater experimentation indicated that the Krill Oil was the one supplement that really made the difference. I think the lack of Omega 3 Fatty Acids was most of the problem but inflammation likely played a role also. One supplement turned my life around. I only wish I would have discovered that about thirty years earlier.
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\r\nDan\r\n

hoots713

\r\n \r\n D Bergy,
\n I am looking for the person you blogged with about lyme a couple years ago (goodsamaritan). If I am correct, you are aware who that person\'s true identity was. I am researching Total Body Modification in Houston and I would like to interview that person. Only if you feel comfortable, would you be so kindly to email me at [email protected] who he or she is. Thanks.
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\nHeidi\r\n

happy2bhere

\r\n \r\n I am one to believe that if you have a great working GUT, all else works, too. I truly believe poor diet = inflammation.
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\nI am looking to purchase some omega3s today from biotics research since I have to reorder my D3. (I read somewhere that fish oil is over processed?)
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\n I feel it\'s important to mix them up a bit tho, so as not to have a wonky ratio.
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\nI have been hearing much about tuna in the oils, lately. I thought tuna was the baddy as far as mercury goes.
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\nThank you Ted_Hutchinson

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\r\n \r\n Activating vitamin D3 requires the presence of MAGNESIUM. Modern intensively industrially produced foods contain less magnesium than just 50 yrs ago. Most adults get less than half the Magnesium RDA. Most would benefit from 100mg magnesium with each meal and before bedtime.\r\n \r\n

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f.luxing right now\r\n

newlife

\r\n \r\n We are "equal opportunity inflammation machines". At the cellular level, we don\'t discriminate between physical trauma, chemical trauma, emotional trauma, etc . . . Trauma is trauma. Stressors of many kinds can trigger inflammation . . . which means there can be just as many different ways to resolve inflammation.\r\n

Ted_Hutchinson

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\r\n Originally Posted by newlife\r\n

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We are "equal opportunity inflammation machines". At the cellular level, we don\'t discriminate between physical trauma, chemical trauma, emotional trauma, etc . . . Trauma is trauma. Stressors of many kinds can trigger inflammation . . . which means there can be just as many different ways to resolve inflammation.

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Indeed but humanity evolved in East Africa where sunlight 12 hrs daily (vitamin d production) is from dawn to dusk and Nightime (melatonin secretion) 12 hrs daily is from dusk to dawn.
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\r\nHumanity living naked outside in daylight and without electric light at night had much higher levels of 25(OH)D and melatonin compared to most humans now.
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\r\nAll their meat and fish was wild caught free range organic so higher in omega 3 than most modern meat/fish.
\r\nAll their veggies and fruit were organically grown and freshly harvested with none of the high tech fertilisers/pesticides modern fast growing higher yielding varieties require and almost certainly had higher magnesium and other mineral content compared with modern varieties.
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\r\nIf humans today attained and maintained the NATURAL anti-inflammatory reserves that would have typically been present in early humans, we would be much better able to deal with life\'s many inflammatory stresses.\r\n

newlife

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\r\n Originally Posted by Ted_Hutchinson\r\n

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If humans today attained and maintained the NATURAL anti-inflammatory reserves that would have typically been present in early humans, we would be much better able to deal with life\'s many inflammatory stresses.

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Definitely.\r\n

Ted_Hutchinson · � #1 � 02-01-2013, 03:05 AM

Depression: an inflammatory illness?

Quote:

Figure 1
Potential pathways through which inflammation may play a part in the pathogenesis of major depression. Inflammation is activated in response to a stressor—endogenous (medical illness) or exogenous (psychological/medication).
This acts as a precipitating factor in those who are vulnerable (predisposing).
This not only precipitates but also perpetuates and maintains the major depressive phenotype by preventing recovery. DAT, dopamine transporter; HPA, hypothalamic–pituitary–adrenal; IDO, indoleamine dioxygenase; SERT, serotonin transporter.

This is an interesting paper discussing the role of inflammation in depression.
Seems to me that restoring the NATURAL anti inflammatory reserves that human DNA evolved with may be helpful for everyone and also help prevent/treat depression.
Humans evolved living near naked outdoor lives and under these circumstances the NATURAL vitamin D level is around the 50ng/ml 125nmol/l mark.
Grassrootshealth chart showing Vitamin D requirements per LB/KG to reach that level.

Activating vitamin D3 requires the presence of MAGNESIUM. Modern intensively industrially produced foods contain less magnesium than just 50 yrs ago. Most adults get less than half the Magnesium RDA. Most would benefit from 100mg magnesium with each meal and before bedtime.

While human DNA was forming and evolving to modern humans ALL the food we consumed were free range organic. The major difference between grass fed pastured meats is their higher omega 3 status and lower omega 6 levels. If we want to restore our anti inflammatory reserves improving omega 3 levels with fish oil or other marine sourced omega 3 alongside a reduction in the amount of omega 6 rich meats and vegetable/seed/grain oils is required.

Human DNA is set to produce 10,000iu of the anti inflammatory Vitamin D3 from dawn to dusk (given full body non burning UVB exposure) and from DUSK TO DAWN it's set to produce the anti inflammatory hormone MELATONIN. There is much that can be done to improve sleep hygiene to maximise melatonin production. f.lux: software to make your life better

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