Quote:
Originally Posted by knightofalbion
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I wonder what they mean by "extremely high doses" and how frequently? I would want to find nicotinamide, instead of niacin, for this function.
Nicotinic acid, also known as
niacin, is converted to nicotinamide
in vivo, and, though the two are identical in their vitamin functions, nicotinamide does not have the same pharmacologic and toxic effects of
niacin, which occur incidental to niacin's conversion. Thus nicotinamide does not reduce cholesterol or cause flushing, although nicotinamide may be toxic to the liver at doses exceeding 3 g/day for adults
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