08-07-2010, 02:25 AM
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Lecturer
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Join Date: May 2009
Posts: 1,698
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Revisiting Dietary Cholesterol Recommendations
Revisiting Dietary Cholesterol Recommendations: Does the Evidence Support a Limit of 300 mg/d?
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The perceived association between dietary cholesterol (DC) and risk for coronary heart disease (CHD) has resulted in recommendations of no more than 300 mg/d for healthy persons in the United States.
These dietary recommendations proposed in the 1960s had little scientific evidence other than the known association between saturated fat and cholesterol and animal studies where cholesterol was fed in amounts far exceeding normal intakes.
In contrast, European countries, Asian countries, and Canada do not have an upper limit for DC.
Further, current epidemiologic data have clearly demonstrated that increasing concentrations of DC are not correlated with increased risk for CHD.
Clinical studies have shown that even if DC may increase plasma low-density lipoprotein (LDL) cholesterol in certain individuals (hyper-responders), this is always accompanied by increases in high-density lipoprotein (HDL) cholesterol, so the LDL/HDL cholesterol ratio is maintained.
More importantly, DC reduces circulating levels of small, dense LDL particles, a well-defined risk factor for CHD.
This article presents recent evidence from human studies documenting the lack of effect of DC on CHD risk, suggesting that guidelines for DC should be revisited.
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Conclusions
The epidemiologic studies and clinical trial results reviewed here suggest that compelling evidence is lacking for limiting cholesterol intake to 300 mg/d. Accordingly, the current US dietary guidelines should be re-evaluated.
Based on recent evidence, the current restrictions on cholesterol have largely and inappropriately been translated into a reduced consumption of eggs, a highly nutritious food.
The fact that most other countries have chosen to not only not limit eggs, but dietary cholesterol itself, indicates that the overall evidence cannot sustain such limitations.
Why not follow their example and accept the challenge of modifying these guidelines?
Well at last we see a move away from the Cholesterol Hypothesis.
I wonder how long it will be before they undertand that Saturated Fat Consumption Still isn't Associated with Cardiovascular disease
Dietary intake of saturated fatty acids and mortality from cardiovascular disease in Japanese: the Japan Collaborative Cohort Study for Evaluation of Cancer Risk Study?
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