02-11-2008, 11:37 AM
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Lecturer
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Join Date: Apr 2006
Location: Propecia, CA
Posts: 1,852
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Artificial Sweetener Linked to Weight Gain
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Three different experiments explored whether saccharin changed lab animals� ability to regulate their intake, using different assessments �the most obvious being caloric intake, weight gain, and compensating by cutting back.
The experimenters also measured changes in core body temperature, a physiological assessment. Normally when we prepare to eat, the metabolic engine revs up. However, rats that had been trained to respond using saccharin (which broke the link between sweetness and calories), relative to rats trained on glucose, showed a smaller rise in core body temperate after eating a novel, sweet-tasting, high-calorie meal. The authors think this blunted response both led to overeating and made it harder to burn off sweet-tasting calories.
�The data clearly indicate that consuming a food sweetened with no-calorie saccharin can lead to greater body-weight gain and adiposity than would consuming the same food sweetened with a higher-calorie sugar,� the authors wrote.
The authors acknowledge that this outcome may seem counterintuitive and might not come as welcome news to human clinical researchers and health-care practitioners, who have long recommended low- or no-calorie sweeteners.
What�s more, the data come from rats, not humans. However, they noted that their findings match emerging evidence that people who drink more diet drinks are at higher risk for obesity and metabolic syndrome, a collection of medical problems such as abdominal fat, high blood pressure and insulin resistance that put people at risk for heart disease and diabetes.
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https://www.physorg.com/news121928361.html
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