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\r\n \r\n Did you ever wonder what�s going on with all those viruses and the numbers attached to them? Since everyone at the U.S. CDC/FDA seems to be gearing up for a new pandemic virus out of China, the H7N9, perhaps we ought to become acquainted with the numerous strains of viruses.
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\nFirst, what do the letters in a virus �name� represent, i.e., the �H� and the �N�? Both represent glycoproteins HA and NA, which are hemagglutinin and neuraminidase, spike-like protrusions on the flu virus surface, which are responsible for attachment and �invasion�.
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\nThere is quite a roster of glycoproteins: 16 HAs and 9 NAs that can or may have the same hosts. However, we have to keep in mind that influenza viruses also have type classifications, viz., A, B, and C. Type C is the mildest; B, which primarily infects humans, can be a real �sickie� but it will never produce type A, which is the pandemic strain.
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\nNow to a listing of glycoproteins, which may be helpful in understanding virus �speak�.
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\nH1, H2, N1, and N2 have the same hosts: humans, pigs, birds
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\nH4, H5, H6, H8, H10 through H16 all have the same host: birds\r\n \r\n
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Old 05-10-2013, 06:54 AM
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Default What do the numbers and letters mean?

Quote:
Did you ever wonder what�s going on with all those viruses and the numbers attached to them? Since everyone at the U.S. CDC/FDA seems to be gearing up for a new pandemic virus out of China, the H7N9, perhaps we ought to become acquainted with the numerous strains of viruses.

First, what do the letters in a virus �name� represent, i.e., the �H� and the �N�? Both represent glycoproteins HA and NA, which are hemagglutinin and neuraminidase, spike-like protrusions on the flu virus surface, which are responsible for attachment and �invasion�.

There is quite a roster of glycoproteins: 16 HAs and 9 NAs that can or may have the same hosts. However, we have to keep in mind that influenza viruses also have type classifications, viz., A, B, and C. Type C is the mildest; B, which primarily infects humans, can be a real �sickie� but it will never produce type A, which is the pandemic strain.

Now to a listing of glycoproteins, which may be helpful in understanding virus �speak�.

H1, H2, N1, and N2 have the same hosts: humans, pigs, birds

H4, H5, H6, H8, H10 through H16 all have the same host: birds
Read more
__________________
"We know that no one ever seizes power with the intention of relinquishing it. Power is not a means; it is an end. One does not establish a dictatorship in order to safeguard a revolution; one makes the revolution in order to establish the dictatorship. The object of persecution is persecution. The object of torture is torture. The object of power is power. Now you begin to understand me." George Orwell
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