Fibromyalgia and CoQ10

[Harry Hirsute]

I've read about some doctors using D-ribose and CoQ10 as part of a holistic protocol for fibromyalgia patients.

Coenzyme Q10 Levels in Patients with Fibromyalgia

In a study involving 37 patients with fibromyalgia, higher levels of markers of oxidative stress were found among patients with fibromyalgia, as compared to healthy controls. In addition, levels of coenzyme Q10 in the plasma were two times higher among fibromyalgia patients, as compared to healthy controls, while levels of coenzyme Q10 in blood mononuclear cells were 40% lower among fibromyalgia patients, as compared to healthy controls.

Fibromyalgia patients were found to have higher levels of ROS production than healthy controls. When coenzyme Q10 was present, a significant reduction in ROS was found. The authors state, "The distribution of CoQ10 in blood components was altered in FM patients. Also, our results confirm the oxidative stress background of this disease probably due to a defect on the distribution and metabolism of CoQ10 in cells and tissues. The protection caused in mononuclear cells by CoQ10 would indicate the benefit of its supplementation in FM patients."

The results of this study suggest that supplementation with coenzyme Q10 may be of benefit to patients with fibromyalgia. Additional research is warranted