Researchers led by Gang Hu at the University of Helsinki set out to examine the associations between coffee consumption and serum GGT with the risk of liver cancer in a large prospective cohort.
Residents of Finland drink more coffee per capita than the Japanese, Americans, Italians, and other Europeans, so Hu and colleagues studied 60,323 Finnish participants ages 25 to 74 who were cancer-free at baseline.
The Finns were included in seven independent cross-sectional population surveys conducted between 1972 and 2002 and followed up through June 2006.
The participants completed a mail-in questionnaire about their medical history, socioeconomic factors and dietary and lifestyle habits. For a subset of participants, clinical data was available, including serum levels of GGT. Data on subsequent cancer diagnoses was collected from the country-wide Finnish Cancer Registry.
Based on their answers to the question: "How many cups of coffee do you drink daily?" the participants were divided into five categories: 0-1 cup, 2-3 cups, 4-5 cups, 6-7 cups, and 8 or more cups per day. After a median follow-up period of 19.3 years, 128 participants were diagnosed with liver cancer.
The researchers noted a significant inverse association between coffee drinking and the risk of primary liver cancer. They found that the multivariable hazards ratio of liver cancer dropped for each group that drank more coffee. It fell from 1.00, to .66, to .44, to .38 to .32 respectively.
"The biological mechanisms behind the association of coffee consumption with the risk of liver cancer are not known," the authors point out.
I was thinking about this.. I wonder why coffee would help the liver? or maybe that is just what they tested.. perhaps it is a general cancer preventative.
I think it's likely due to it's phytochemical composition (chlorogenic acid is one strong candidate). Also, remember that coffee is, for many people, the greatest source of antioxidants that they consume in their daily diet. This is both a testament to the java and the poor diets many people have adopted.
May 25, 2007 – The more coffee men drink, the lower their risk of gout. At least four cups a day lower gout risk by 40%, a Canada/U.S. study shows.
Gout starts with a buildup of uric acid in the blood. This results in deposits of uric acid crystals in the joints and surrounding areas, causing swelling and intense pain.
The new study is based on data from nearly 46,000 male medical professionals enrolled in the Health Professionals Follow-Up Study. Over 12 years, 757 of these men developed gout, report Hyon K. Choi, MD, DrPH, of the University of British Columbia in Vancouver, and colleagues.
Because the men filled out detailed diet questionnaires, Choi's team was able to track the men's self-reported use of coffee and tea.
They found that the more coffee the men drank, the less likely they were to have gout.
Drinking one to three cups of coffee a day lowered gout risk by only 8%. But drinking four or five cups a day dropped gout risk by 40%. And true coffee addicts -- those who drank six cups a day or more -- had nearly a 60% lower risk of gout.
NEW YORK (Reuters Health) - Coffee and tea lovers may have a slightly reduced risk of developing kidney cancer, research hints.
The findings, based on an analysis of 13 previous studies, suggest that coffee and tea may be protective against kidney cancer, while milk, soda and juice seem to have no effect one way or the other.
Across the studies, people who drank three or more cups of coffee a day were 16 percent less likely to develop kidney cancer than those who averaged less than a cup per day. And those who sipped just one 8-ounce cup of tea each day had a 15 percent lower risk of the disease than non-drinkers.
The findings appear in the International Journal of Cancer.
I appreciate your post Harry, although I still don't understand how this could be so, even with those findings. Xanthines convert to UC, UC can be responsible for Gout, the two factors combining to form a lower Gout Risk makes no sense to me.
The findings don't say how this is piossible, just that it is reportedly so. What I mean is there's no what's called Mechanism Of Action, explained here.
It's like if someone did a survey, to find if Anemia could be prevented, by people adding Whole-grain Beef Sandwiches to their diet, and then not telling them the correlation between the Heam Iron, Non-Heam Iron and Anemia prevention, and expecting people to believe it, by telling them how the data was analysed.
I'm not saying you're expecting anyone to believe what you posted, as it's not your study, just your proffering of scientific reasearch, and of course your postings are well researched, and appreciated, but this study tells people how the results were obtained, but not how the results were physically possible, I.E. how the participants bodies produced these outcomes, in lieu of what I said about Xanthines, UC and Gout.
There's nothing to say how the body utilised the Coffee, to make the Gout risk lower, rather than higher.
Coffee and Liver Cancer Risk
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On the other hand, there's this:
Linear Mode
