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Old 01-18-2016, 08:47 PM
tom tom is offline
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Default Low Testosterone and Fatigue?


I have a simple question surrounding fatigue and low testosterone.

I have always thought that if you are suffering from adrenal fatigue, when the initial stages of fatigue set in (the hyper-cortisol stage), excess cortisol robs your body of DHEA (Dehydraepiandrosterone) used to produce testosterone. Thus, a hyper-cortisol state indirectly reduces testosterone.

Having said this, I still see allot of articles on the web suggesting that Low Testosterone can lead to fatigue??

My question is this: Is it both true that low testosterone can lead to fatigue and that fatigue can also lead to low testosterone?

I can explain how fatigue leads to low T but not the other way around. Can anyone help? Thanks
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Old 03-10-2016, 06:22 PM
Chocho18 Chocho18 is offline
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Default Personal Research

I am currently experiencing low testosterone who's primary symptoms are fatigue. It might work in both directions although the exact mechanism is not clearly understood. Sadly research in this area is somewhat uncommon, as most of the research is scewed towards low fertility as being the primary symptom. If you think you are experiences this, PLEASE see an endocrinologist for blood tests. Treating yourself without a proper diagnosis for this is expensive, and increases likelyhood of side effects.

One predominate theory on how testosterone can cause fatigue comes from the fact that there are receptors in our brains which recognizes hormones. See: http://blogs.plos.org/neuro/2016/02/...ne-beyond-sex/ for a really interesting article for a study on how low testosterone can affect rat behavior.

As for fatigue causing low testosterone, maybe. The wikipedia article on this (@https://en.wikipedia.org/wiki/Androgen#Androgenic_impact_of_exercise) provides some papers which might seem to indicate this. However, there are some debate apparently at 1) this affect being real (http://www.ncbi.nlm.nih.gov/pubmed/18608830) and 2) whether the most common method for testing testosterone in these studies is valid (http://www.ncbi.nlm.nih.gov/pubmed/18608830).
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