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Old 11-09-2012, 10:41 AM
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Default Breast Cancer current recommended diet requires reconsideration

Weight Gain, Metabolic Syndrome, and Breast Cancer Recurrence: Are Dietary Recommendations Supported by the Data?
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traditional dietary recommendations of limiting fat while favoring dietary carbohydrates may be a suboptimal strategy for improving nearly every metabolic risk factor for breast cancer recurrence, including decreasing adipose tissue, serum glucose, serum insulin, and inflammatory factors, while increasing HDL and insulin sensitivity.
The full text of the paper is free at the link provided.
While the paper is discussing the diet in relation to Breast Cancer prognosis the ideas being discussed would be equally suitable for breast cancer progression.
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Old 11-09-2012, 11:12 AM
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In paragraph 2.1 of the paper above they say
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Fat cells secrete the inflammatory mediators tumor necrosis factor alpha (TNFα), interleukin 6 (IL-6), and retinol-binding protein-4 (RBP4). TNFα has been shown to promote breast cancer growth through the activation of several intracellular molecular pathways, including MAPK, kappa B (NF-kappa B), and the PI3-K/Akt pathway
Readers may not be aware Vitamin D3 works as an antiflammatory agent inhibiting production of TNFα with the most powerful inhibition of inflammation occurring at 50 ng/ml. ~125nmol/l.
A recent paper reporting on 25(OH)D levels in hunger~gatherer peoples in East Africa showed natural 25(OH)D levels reach equilibrium around that level.

UK readers can now get 5000iu vit D3 off Amazon UK for less than 10 360 capsules and CityAssays Birmingham NHS Path lab Offer postal 25(OH)D tests for 25 (less if you bulk buy and share with friends)

Allow 3 months using 5000iu/daily before retesting 25(OH)D then adjust dose 1000iu more if 25nmol/l or more below target and 1000iu/d less if 25nmol/l or more above target.

Efficacy of omega-3 fatty acid supplementation on serum levels of tumour necrosis factor-alpha, C-reactive protein N Short-term omega-3 fatty acid supplementation (3 g/day for eight weeks) can decrease the serum levels
of TNF-α and IL-2 in diabetic patients

Last edited by Ted_Hutchinson; 11-09-2012 at 01:31 PM.
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Old 11-09-2012, 01:16 PM
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Quote:
IL-6 was independently correlated with shorter survival
IL-6 was also found to be predictive of nodal involvement, tumor size at initial diagnosis, progression, and experiencing multiple metastatic sites

Curcumin (TURMERIC) inhibits IL-6

Okinawans also drink copious amounts of tumeric tea daily. It is also used as a spice for curries, soups and fish dishes. Tumeric is originally from India and a member of the ginger family. Scientific evidence has shown tumeric to possess strong antioxidant, anti-microbial, anti-cancer and anti-inflammatory actions.

recipe for Turmeric tea there are lots of these online so if you don't like this one try some of the others till you find one you're happy to drink 4 times daily.
or consider
Healthyfellow Best Curcumin Supplement
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Old 11-09-2012, 01:32 PM
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Quote:
circulating levels of CRP and serum amyloid A were associated with reduced disease-free and overall survival.
High levels of these inflammatory markers were also associated with a doubling of the risk of recurrence and mortality in a cohort of women diagnosed with breast cancer
There was an inverse correlation between serum 25(OH)D.....and hsCRP

Likewise, curcumin prevented the increase of SBP, CRP, TNF α, D-dimer and PAI-1.

Postoperative C-reactive protein, malondialdehyde, and N-terminal pro-B-type natriuretic peptide levels were also lower in the curcuminoid than in the placebo group...... The antioxidant and anti-inflammatory effects of curcuminoids may account for their cardioprotective effects shown in this study.
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Old 11-09-2012, 01:37 PM
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Melatonin ameliorates low-grade inflammation and oxidative stress in young Zucker diabetic fatty rats.
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Melatonin lowered IL-6 10% TNF-α 10%, and CRP 21%,
It's no wonder that shift work (lack of melatonin) increases BC incidence and mortality.
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Old 11-10-2012, 04:19 AM
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And lugols iodine supplementation eliminates fibrocystic breast disesase, which is a predisposting factor to getting breast cancer.

I think it would be safe to say that iodine can eliminate some inflammatory issues.
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Old 11-10-2012, 09:10 AM
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Apigenin,a flavonoid found in celery and parsley, has been found to help in BC caused by Progestin Hormone therapy.

http://www.lef.org/newsletter/2012/0...ign=2012Wk38-2

If you dont like the taste of celery or Parsley you can get an Apigen supplement(derived from grapefruit)from:

http://www.swansonvitamins.com/swans...-50-mg-90-caps

in the UK:

http://www.healthmonthly.co.uk/swanson_ultra_apigenin

.
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breast cancer, insulin insensitivity, metabolic syndrome, obesity
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