Animal Products May Increase the Risk of Endometrial Cancer

[Iggy Dalrymple]

Summary# 44973
Topic: Intake of Animal Products May Increase the Risk of Endometrial Cancer, while Intake of Plant Products May Decrease the Risk
Keywords: ENDOMETRIAL CANCER - Diet, Nutrients, Animal Products, Plant Products, Saturated Fat, Monounsaturated Fat, Retinol, Beta-carotene, Vitamin C, Vitamin E, Fiber, Vitamin B1, Vitamin B2
Reference: "Nutritional factors in relation to endometrial cancer: A report from a population-based case-control study in Shanghai, China," Xu WH, Dai Q, et al, Int J Cancer, 2007 Jan 17; [Epub ahead of print]. (Address: Department of Epidemiology, Fu Dan University School of Public Health, Shanghai, People's Republic of China).
Summary: In a population-based case-control study involving 1,204 subjects with newly diagnosed endometrial cancer and 1,212 controls, higher intake of energy from animal products, along with a high proportion of energy from protein and fat, was found to be associated with an increased risk of endometrial cancer, while dietary intake of retinol, beta-carotene, vitamin C, vitamin E, fiber, and vitamin supplements were found to be associated with a reduced risk of endometrial cancer. The odds ratios for endometrial cancer were 2.0 for high animal protein intake, 1.5 for high animal fat intake, 0.7 for high plant protein intake, and 0.6 for high plant fat intake. Furthermore, high intake of saturated and monounsaturated fats was associated with an increased risk of endometrial cancer. No association was found for polyunsaturated fat, dietary vitamin B1 or dietary vitamin B2 intakes. The authors conclude, "Our findings suggest that associations of dietary macronutrients with endometrial cancer risk may depend on their sources, with intake of animal origin nutrients being related to higher risk and intake of plant origin nutrients related to lower risk." http://www.vitasearch.com/get-clp-summary/36003

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