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Old 07-23-2009, 07:57 AM
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Default Curcumin May Prevent Clogged Arteries

http://www.medicinenet.com/script/ma...iclekey=103981


Quote:
Study Shows Ingredient in Curry Spice May Reduce Fatty Deposits in Arteries

July 20, 2009 -- The compound that gives curry spice powder its yellowish color may protect arteries from fatty buildup, new research in mice shows.

Curcumin, the main ingredient in the curry spice turmeric, is a naturally occurring antioxidant known as a polyphenol. Polyphenols are found in plants that have anti-inflammatory and other protective properties.

Previous studies in rats showed that curcumin had the power to prevent heart failure. Turmeric-based compounds have also been touted as potential treatments for Alzheimer's, arthritis, and breast cancer.

The current study suggests curcumin may thwart the development of atherosclerosis, or clogged arteries, a key risk factor for heart attacks and strokes.

Researchers in France fed 20 mice a diet supplemented with curcumin or a comparison diet not supplemented with curcumin. After 16 weeks, mice fed on the curcumin-based diet had a 26% reduction in fatty deposits in their arteries compared to mice on the comparison diet.

In addition, curcumin appeared to alter the genetic signaling involved in plaque buildup at the molecular level.

The findings are being presented this week at the American Heart Association's Basic Cardiovascular Sciences Annual Conference in Las Vegas.
Curcumin has a low bioavailability and capsules are best bought containing bioperine, a pepper which increases absorption. Its also advisable to break the capsule open and mix it with coconut oil, or extra virgin olive oil, in a spoon to further increase absorption.
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Old 07-23-2009, 10:05 AM
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No doubt about it. Curcumin is magic. Long list of benefits.

This site is a vendor; but they have a huge amount of references to reports.
http://www.turmeric-curcumin.com/

Quote:
It has been identified in pharmacology as:
Antibacterial Anti-inflammatory Antivral Diuretic Anti-oxidant Anti fungal Anti yeast Carminative Antiallergenic Anti-spasmodic Anti-tumour

Turmeric and Curcumin traditionally been used to support those suffering from pain and inflammation:
Acne Digestive Disorders Allergies Gallbladder Problems Ascites Liver Damage Auto-immune Disorders Liver Disorders Burns Skin Rashes Chicken Pox Tumours Diabetes Ulcers and Eye Problems such as Cataracts

If that is not enough, Turmeric has been used for thousands of years by Indian Women to make their skin beautiful and blemish free.
No side effects have been found taking high doses of Curcumin; rare cases of stomach upset or diarrhoea may be resolved by temporally, reducing the dosage and taking with food.

http://www.curcuminhealth.info/
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Old 08-01-2009, 04:28 AM
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This is what Dr. Mercola has to say about it.

How this Ancient Spice Originated Thousands of Years Ago

That is one of the reasons I traveled over 15,000 miles to India last year -- to find a high quality source of these herbs. During this trip to India, I witnessed firsthand how this Ayurvedic holistic approach and organic processes work in unison.

And of the many herbs and spices I studied, one in particular caught my immediate attention. The herb is called turmeric, and it can provide you whole person health benefits:
Supports your healthy joint function*
Promotes your radiant skin*
Helps improve your digestion*
And much more...

Now, there is some debate about the timing of turmeric's first use as a healthy spice.
But one thing is certain. Thousands of years ago, people in India and China used the spice. In fact, some stories suggest usage dates back 10,000 years in India when they say Lord Rama walked the earth.

And the ancient Polynesians carried turmeric with them on their incredible voyage across the Pacific Ocean to Hawaii. Today, Hawaiians still use this spice -- known to them as Olena.

While in China, Marco Polo in 1280 AD recorded information on turmeric in his diary:
"There is also a vegetable which has all the properties of true saffron, as well the smell as the color, and yet it is not really saffron."

So, turmeric has been used as a substitute for saffron (an old world spice) in Europe for over 700 years.

One of the main healthful ingredients in turmeric is curcumin (a curcuminoid), which gives turmeric its yellow color. Western scientists first isolated the curcumin molecule in 1815, obtained its crystalline form in 1870, and determined its overall structure in 1910.

Curcumin can potentially benefit you by:

Promoting your immune system against stress*
Helping maintain your healthy digestive system*
Supporting your healthy bones, joints, and overall skeletal system*
Helping you maintain cholesterol levels that are already within the normal range*
Promoting your healthy blood and liver functions*
How Turmeric Provides Antioxidant Nutrients*

You probably know that antioxidants are important nutrients in supporting your health.
They help you slow down free radical damage that can seriously damage your cells, organs and DNA
Turmeric helps protect your cells -- and helps you counteract this process with its antioxidant content.*
The antioxidant content within turmeric comes from active compounds called curcuminoids.
These curcuminoids deliver antioxidants that may be:
5 to 8 times stronger than vitamin E -- and also stronger than vitamin C
3 times more powerful than grape seed or pine bark extract
Strong enough to scavenge the hydroxyl radical -- considered by many to be the most reactive of all oxidants*
I believe antioxidants are your body's #1 way to neutralize free radicals and help you potentially slow down the signs of normal aging.*
Oxidation by free radicals can damage cells and DNA -- and thus impact your aging process* -- something we all would like to put the brakes on.
Antioxidants are also key nutrients in:
Supporting your memory function*
Promoting your heart health*
Boosting your immune system*
So, I can't say enough about the importance antioxidants play in promoting your overall health.* And turmeric is another excellent source of antioxidants for you.
Why this Herb Can Help Enhance Your Outer Beauty*

Speaking of antioxidant nutrients and their potential to impact the aging process, some of the first aging signs you may see as you get older are changes to your skin.

Well, the organic ingredients found in turmeric can help promote your healthy skin.*
How does it work?
Curcuminoids support important blood and liver functions, healthy joints, and your overall well-being.* This in turn helps promote your radiant, supple skin.*
Turmeric has been considered to be ‘skin food' for thousands of years in India and other cultures.*
Turmeric helps you:
Cleanse your skin and maintain its elasticity*
Provide nourishment to your skin*
Balance the effects of skin flora*
So, turmeric can act as your one-two punch against normal aging with its skin promotion and antioxidant capabilities -- outer beauty and inner purity.*
Your Triple-Action Cellular Booster and Adaptogen*

Another potential advantage from turmeric usage involves the smallest living things within you -- your cells.
Turmeric can assist your cells in three ways, by:

Helping you neutralize substances that can cause cellular stress*
Maintaining your cells' integrity when threatened by occasional environmental stressors*
Providing the antioxidants you need to help support your cells against excessive oxidation and free radicals*
And turmeric is also recognized as an adaptogen -- helping to support your body against stress and providing immune system support.*
How this Ancient Spice has Become
Embedded in India's Ayurvedic Practice

Turmeric, like other herbs and spices, is a principle herb in Ayurveda -- India's ancient holistic health system. Ayurveda means "knowledge of life" -- with herbs lying at the very heart of Ayurvedic practice.
And turmeric has multiple uses within Ayurveda, including blood cleansing and maintaining healthy skin.*
In Ayurvedic terminology, turmeric includes the following:
Verdana sthapana -- promotes your healthy nervous system and helps you with occasional discomfort*
Sangrahani -- supports your absorption of vitamins and minerals*
Anulomana -- helps you in purging out wastes and building healthy blood*
Rakta stambhaka -- promotes the wellness of your circulatory system*
And this is pretty much the tip of the iceberg when it comes to Ayurvedic turmeric uses.
What does all this mean to you?
Simply, turmeric has been used in Indian culture for thousands of years for a multitude of health-promoting reasons.* And an estimated 500 million Indians still use the spice today.
What are Your Sources for Turmeric?

So by now, you might be wondering about potential sources of turmeric.
Well, you could already know you can find it in the spice aisle of your local grocery store. But as I mentioned earlier, I would not recommend you use your local grocery store as a high-quality source of organic herbs and spices.
Even though there may be some good spices available there, it is very difficult to verify their purity and potency.
And also, the turmeric powder you buy in your store is a spice. It doesn't necessarily come from high-quality organic herbs -- and is not produced using certified organic processes. So you risk missing out on its healthful benefits.
Plus, with store-bought turmeric powder, you'll probably just use it once in awhile to cook with -- and not on a daily basis to consistently take advantage of the benefits it offers.
So, what are your other choices?
I would recommend searching for a high-quality, 100% organic-based turmeric supplement.
However, there are some things you need to watch out for when choosing a turmeric supplement.
Avoid Unnecessary Fillers, Additives, and Excipients

When I did my own research on available turmeric supplements, I found a surprising number of choices.
In addition to the curcumin and curcuminoid ingredients, I r found many products that had other questionable ingredients in the form of fillers, additives, and excipients. An excipient is a substance added to the supplement as a processing or stability aid.
One ingredient, magnesium stearate (also know as stearic acid), is a potentially toxic metal additive from pill production.
Another ingredient I found in many turmeric supplements, Dibasic Calcium Phosphate (DCP), may even inhibit the absorption of essential minerals within your system.
There are others you may find as well, but the bottom line here is... you don't want or need these ingredients in your turmeric supplement. Some pose potential health risks -- and really are unnecessary.
Make Sure Your Herbal Supplement Comes from a
Certified Organic Producer Committed to Quality Processes

The key to delivering an organic-based turmeric supplement rests in the manufacturer's commitment to quality and excellence.

In fact, I believe that without these quality processes in place, it really doesn't matter what organic herbs are harvested. You simply won't end up with a top-notch consistent organic formula. And in turn, you won't receive the maximum potential value of the herb.
So, it's important for you to highly scrutinize and research the manufacturer's credentials.
And you may not be able to stop with the manufacturer alone. Keep in mind, the total organic process involves planting, cultivation, selective harvesting, and then producing and packaging the final formula.
Here's the type of certifications I recommend you look for:
Hazards and Critical Control Points (HACCP) -- International food safety certification that World Health Organization (WHO) standards are met
Safe Quality Food (SQF) -- HACCP-based food safety and risk management system covering the identification of food safety, quality risks, and the validation and monitoring of control measures
Good Manufacturing Practices (GMP) -- International certification verifies all required practices necessary for an effective food safety program are followed
International Organization for Standardization (ISO) 9001:2000 -- International standard for quality, safety, ecology, economy, reliability, compatibility, inter-operability, efficiency, and effectiveness
Orthodox Union (OU) Kosher -- Certifies compliance for Kosher observers and followers
International organic certificationssuch as: USDA, EU, and NSOP (India)
Use This Checklist When Sourcing Turmeric

To take advantage of all the great benefits turmeric has to offer you, I've created a checklist on what you should look for in a turmeric supplement.
Whatever you do, don't settle for second best.
Now, here's my checklist to help you find the best turmeric source:
Contains only 100% certified organic ingredients -- Turmeric extract with at least 95% curcuminoids
Comes in supplement form -- Don't rely on your typically low quality and unpredictable local grocery store spice. Additionally when you heat the spice during cooking many of the beneficial properties are lost.
Avoids fillers, additives, and excipients -- No need for questionable "other ingredients" in the formula
Provides a vegetable capsule -- Avoid gelatin-based capsules whenever possible
Is produced by a certified organic manufacturer with high-quality organic and safe production practices -- Don't settle for second best here!
13 Ways this Ancient Herb Can Help You
Spice Up Your Life (and Your Health*)

Let me summarize a few of the ways this 100% certified organic-based Turmeric can spice up your whole person:
Boosts your antioxidant protection against free radicals*
Helps promote your healthy skin*
Supports your overall eye health*
Provides you immune system support*
Aids your skeletal system and joint health*
Encourages your healthy liver function*
Helps you maintain healthy cells with support against free radicals*
Balances the health of your digestive system*
Aids you in support of healthy blood and your circulatory system*
Helps you maintain normal cholesterol levels to support your cardiovascular system*
Assists your neurological system's healthy response to stress*
Promotes a healthy female reproductive system*
Helps you maintain blood sugar levels already within the normal range*
And more...
Millions of people use turmeric on a daily basis in their lives today. In India alone, up to 500 million people use it in one form or another every day.
Isn't it time you gave your body what it deserves?
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Old 02-16-2010, 12:47 PM
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Default May also treat/prevent colon cancer as well.

Curcumin: a novel nutritionally derived ligand of the vitamin D receptor with implications for colon cancer chemoprevention.
Quote:
The nuclear vitamin D receptor (VDR) mediates the actions of 1,25-dihydroxyvitamin D(3) (1,25D) to regulate gene transcription.
Recently, the secondary bile acid, lithocholate (LCA), was recognized as a novel VDR ligand.
Using reporter gene and mammalian two-hybrid systems, immunoblotting, competitive ligand displacement and quantitative real-time PCR, we identified curcumin (CM), a turmeric-derived bioactive polyphenol, as a likely additional novel ligand for VDR.
CM (10(-5) M) activated transcription of a luciferase plasmid containing the distal vitamin D responsive element (VDRE) from the human CYP3A4 gene at levels comparable to 1,25D (10(-8) M) in transfected human colon cancer cells (Caco-2).
While CM also activated transcription via a retinoid X receptor (RXR) responsive element, activation of the glucocorticoid receptor (GR) by CM was negligible.
Competition binding assays with radiolabeled 1,25D confirmed that CM binds directly to VDR.
In mammalian two-hybrid assays employing transfected Caco-2 cells, CM (10(-5) M) increased the ability of VDR to recruit its heterodimeric partner, RXR, and steroid receptor coactivator-1 (SRC-1).
Real-time PCR studies revealed that CM-bound VDR can activate VDR target genes CYP3A4, CYP24, p21 and TRPV6 in Caco-2 cells.
Numerous studies have shown chemoprotection by CM against intestinal cancers via a variety of mechanisms.
Small intestine and colon are important VDR-expressing tissues where 1,25D has known anticancer properties that may, in part, be elicited by activation of CYP-mediated xenobiotic detoxification and/or up-regulation of the tumor suppressor p21.
Our results suggest the novel hypothesis that nutritionally-derived CM facilitates chemoprevention via direct binding to, and activation of, VDR.
Basically this study is saying that Curcumin (turmeric) activates the Vitamin D receptor effectively. This will be of benefit to those who report they cannot take effective amounts of D3 although whether they will stomach up to 8g daily Curcumin is another story. (personally I'm sticking with the D3) It will also be useful for people with colon cancer as there is the strong possibility that D3 taken orally may not pass through the digestive system as it may be all absorbed before reaching the colon.

I usually use a teaspoon of turmeric in a curry sauce for 4 servings so per person that would be less than 1g curcumin a portion. I think you'd have to be using capsules to consume effective amounts of curcumin if you were considering it as alternative or supplementary to Vitamin D3.
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Old 02-16-2010, 03:11 PM
D Bergy D Bergy is offline
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I take Turmeric every day. It is in the top five supplements in my book.

It is hard to even list all of the benefits of this one herb, there are so many.

Ginger has similar but somewhat different properties, and also helps absorption of other supplements including Turmeric.

Dan
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Old 02-16-2010, 04:36 PM
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I use to take it in oil all the time then I feel out of practice. Thanks for bringing this post up again, Dan. It is just what I needed to see to help a friend who needs this stuff and she can't swallow pills!
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Old 02-18-2010, 01:11 PM
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Quote:
Originally Posted by Arrowwind09 View Post
I use to take it in oil all the time then I feel out of practice. Thanks for bringing this post up again, Dan. It is just what I needed to see to help a friend who needs this stuff and she can't swallow pills!

You can get turmeric extract in capsules. Try using that in a sauce in place of the turmeric.

Ted, throw us some curry recipes.
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Old 02-18-2010, 01:58 PM
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Quote:
Originally Posted by saved1986 View Post
You can get turmeric extract in capsules. Try using that in a sauce in place of the turmeric.

Ted, throw us some curry recipes.
Mamta's kitchen this has lots of genuine Indian curry recipes.
Mamta also has a forum where you can ask questions and get a reply if you don't understand or haven't got all the ingredients and want to know what you could substitute.
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Old 02-18-2010, 02:34 PM
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Ted updated the thread, and I am glad he did, because this is one thing that can benefit almost anyone, for long term health.

Dan
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Old 03-23-2010, 07:26 AM
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I am dying to try something called phal! It is the suppose to be the hottest of the curries. I know at Indian grocery stores you can get pickles: (not the US kind, but pickled mango, lime, garlic and even turmeric). I am going to cleveland akron this weekend (actually kent state, to party hardy) and am doing an indian lunch with a friend. I will google indian gorcery stores and try and pick up some pickled turmeric.
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Old 04-07-2010, 12:39 PM
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I've been taking at least 500 mg everyday for about four years now. At first, when I was first told about it I took it in the form of Curcumine w/piperine but now I just take it in Turmeric form. It is definately a "wonder herb" and the previous posts attest to that. I sure hope it's doing that arterial cleaning. To me, I wouldn't go without Turmeric and fish oil.

Last edited by Naturalman; 04-08-2010 at 08:55 AM.
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Old 04-10-2010, 02:41 PM
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We have been using it for quite a while now too. I have increased my husbands dose to 1000mg per day as studies show it thwarts some of the nasty chemical effects of smoking. But we do use biopeperine with it. Studies show it is absorbed much better if you use it.. I purchases a separate biopeperine pill to take with products that don't have it included... also, biopeperine is noted to increase absorption of other nutrients you might be taking in pill form also, including ALA.

So why not just load on the black pepper?
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Old 04-10-2010, 04:24 PM
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Quote:
Originally Posted by Arrowwind09 View Post
We have been using it for quite a while now too. I have increased my husbands dose to 1000mg per day as studies show it thwarts some of the nasty chemical effects of smoking. But we do use biopeperine with it. Studies show it is absorbed much better if you use it.. I purchases a separate biopeperine pill to take with products that don't have it included... also, biopeperine is noted to increase absorption of other nutrients you might be taking in pill form also, including ALA.

So why not just load on the black pepper?
Arrowwind09,
Don't quote me on this but I think I've read that the body does not assimilate black pepper, at least not readily. The piperine is a constituant of the black pepper that increases absorption several times faster than taking the curcumin (or whatever) alone.
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Old 04-10-2010, 04:52 PM
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"Piperine, is a patent-pending form of "Bioperine" which has been proved in medical trials and research to enhance the body’s natural thermogenic activities. Thermogenesis, the process of generating energy in the cell, enables the body to properly utilize the foods and nutrients taken in daily. It sets the stage for the appropriate activities that lead to digestion and subsequent intestinal absorption. Piperine increases thermal energy sufficiently to "Jump Start" so to say, the operation related to Thermogenesis. This increases the metabolic process that in turn creates a demand for the nutrients necessary for metabolism.
Because black pepper and Piperine are not identical, one having to be processed by several steps in a laboratory, the same effects cannot be achieved by merely increasing ones use of the black pepper spice. Instead, purified Piperine extract is needed to ensure that the bioavailability enhancing properties are utilized for the right and appropriate nutrient absorption levels as when you were younger." www.cochranfoundation.com/reports/piperin.htm
Also, many sites claim that bioperin (piperine or biopiperine) can increase assimlation by 2 thousand percent. Amazing. Also, there are several sites that claim that increasing the black pepper can accomplish the same thing. ?????????
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Old 04-11-2010, 08:52 AM
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Lightbulb Mamtas Kitchen!

Thanks Ted, for the link to Mamtas Kitchen. Some great sounding and
interesting looking recipes on it. Looks good for some new possibles!
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