I don't understand how anyone can read the above paper and come to that conclusion.
Unless you make some effort to correct the problem caused by mitochondrial dysfunction you'll simple end up putting on weight again because the trouble that causes the weight accumulation, the lack of energy and the increased appetite hasn't been changed.

"Insanity, Is doing the same thing over and over again and expecting a different result."

I don't know why anyone suggests eating 7x daily. As hunter gatherer's early humans would have feasted when prey was freshly caught and had periods of famine while hunting the next prey.
Our metabolic system is geared to dealing with calorie excess followed by calorie deprivation. So we load up our fat cells then need time to unload those fat storage cells. By eating 7x daily you are actively preventing the release of stored calories from fat cells.

The longer you leave eating between meals the more chance you have of burning stored fat reserves.

Intermittent fasting is more like the way of eating human DNA is geared towards.

We need to include FAT at every meal as that is one of the main triggers of the satiety hormones. The more you messages get to the brain to indicate you are full and don't need to eat the easier it is to go without food without feeling hungry or deprived and the more you get to rely on the stored calories in fat tissue.

If you want to burn your bodies fat stores you have to restore the metabolic flexibility that allows your system to burn both glucose and fat and switch fuels quickly and easily. Eating 7x daily prevents fuel swapping and locks your body into glucose burning mode only hence making your weight loss harder.

Does anyone think that wild animals have practice aerobic exercise or calorie controlled meals to stay fit.
If wild animals can naturally achieve peak fitness and remain slim without the advice of health professionals what reason do you have for thinking the human animal is any less able to manage to self regulate diet when eating those foods we evolved to consume?

Perhaps it would be wise to check how long your doctor spent learning about diet/exercise during their medical training. The length of training most receive can be measure in minutes rather than hours or day.

It's precisely because doctors are so uneducated and lack the understanding of metabolism that we are in the mess we are currently in.

It it BECAUSE health professionals are giving out misleading and downright dangerous advice that year on year we have MORE AND MORE diabetics, cancer victims and heart disease.

Where for goodness sake is the evidence that doing what doctors tell you helps lower your risk of illness. May I remind you this is a NATURAL medicine forum and how many health professionals actually understand how NATURALLY the body regulates itself.

How many health professionals UNDERSTAND the natural roles of vitamin D3, magnesium omega 3 or melatonin?

I actually posted this on my facebook wall...

For real Ted i love your answers always wise and as far as im concerned correct simply bcuz you make sense...

And ive been to enough doctors in my life to know for a fact that they rarely/never make sense...they just confuse you so that when you leave their office you have more questions than you did walking in.

oh and i love the ''human animal'' part hahaha it put a smile on my face