Already taking a daily B-50 complex, but decided to go out today and pick up some sublingual vitamin B-12 to take every couple of days or so in addition to that. I went with Solaray brand 2,000mcg. Adding the B-12 after reading this article...

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"We can judge the heart of a man by his treatment of animals." ~Immanual Kant~

Vitamin B12 - Methylcobalamin is the active form of Vitamin B12
Vitamin B12 - Cyanocobalamin requires an enzyme in the gut to change it to the active form therefore if you haven't the "intrinsic factor" you MAY be wasting your money.
It's helpful to absorb some in the oral cavity as sometime the digestive system doesn't absorb it.
That study Briffa was talking about the guys taking an ordinary multi that contained ordinary cheapo B12 (Cyanocobalamin) actually didn't do any better with extra B12. so if you've already got B12 in a multi it MAY NOT improve matters taking an extra amount.
Do make sure you are getting plenty of CHOLINE in your diet.
Choline-rich diet tied to sharper memory and I'm sure I don't have to remind anyone low vitamin d status also is linked to the mild cognitive impairment which often precedes dementia.

B12 should be absorbed directly into the bloodstream. Sub-lingual, nasal gel or injections by doctors are the most effective forms of B12. B12 tablets which are meant to be swallowed, dispersing through the digestive tract, are likely to cause diarrhea and will likely not be assimilated by the body--as Ted said, a waste of money.

I've been doing B12 injections for a while now. I really like them and can feel the difference. I hope to help prevent deterioration of the nervous system as I age and of course it is only part of the plan.. I take 10mg per injection about once a month.

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We should be aware though that This [oral] dose is as effective and possibly superior to a parenteral [shots] regimen in all causes of cobalamin deficiency because 1 to 2% of an oral dose is always absorbed by diffusion.

Well, be that as it may, I have noticed significant clinical changes with injection especially when it eliminated my long standing chronic hip pain from a fall. Oral did nothing, but then I didn't take 10mg oral either.. Yuck.. to much to deal with.

I think that high injection dosages do more than just mitigatge a cobalamine deficiency. It perhaps force starts other process... cant say for sure, hence it works more on a medicine level rather than a supplement level.

I still think a steady state is better than swings from high to low.